Intersubject synchronization of cortical activity during natural vision. Hasson, U., Nir, Y., Levy, I., Fuhrmann, G. Generation and evaluation of a cortical area parcellation from resting-state correlations. Function in the human connectome: task-fMRI and individual differences in behavior. Dynamic reconfiguration of cortical functional connectivity across brain states. Whole-central nervous system functional imaging in larval Drosophila. Global brain dynamics embed the motor command sequence of Caenorhabditis elegans. Dimensionality reduction for large-scale neural recordings. Measures of degeneracy and redundancy in biological networks. Noise during rest enables the exploration of the brain’s dynamic repertoire. Intrinsic and task-evoked network architectures of the human brain. Reconfigurable task-dependent functional coupling modes cluster around a core functional architecture. Dynamic models of large-scale brain activity. These results advance our understanding of functional brain organization by emphasizing the interface between neural activity, neuromodulatory systems, and cognitive function.īreakspear, M. The axes of the low-dimensional neurocognitive architecture aligned with regional differences in the density of neuromodulatory receptors, which in turn relate to distinct signatures of network controllability estimated from the structural connectome.
Flow within this attractor space was associated with dissociable cognitive functions, unique patterns of network-level topology, and individual differences in fluid intelligence. We found that neuronal activity converged onto a low-dimensional manifold that facilitates the execution of diverse task states. Here we investigated the spatial, dynamic, and molecular signatures of system-wide neural activity across a range of cognitive tasks. Despite recent progress, the neurobiological mechanisms responsible for this dynamic system-level integration remain poorly understood. The human brain integrates diverse cognitive processes into a coherent whole, shifting fluidly as a function of changing environmental demands.